Table 4.
Comparing the serum anti-JMJD6 antibody (s-JMJD6-Ab) levels between healthy donors (HD) and patients with acute myocardial infarction (AMI) or diabetes mellitus (DM).
| Sample Information | HD | AMI | DM |
|---|---|---|---|
| Total sample number | 128 | 128 | 128 |
| Male/female | 72/56 | 105/23 | 72/56 |
| Age (median ± SD) | 57.0 ± 5.6 | 61.0 ± 8.5 | 60.0 ± 9.2 |
| Patient group | Type of value | s-JMJD6-Ab | |
| HD | Median | 28,808 | |
| Cutoff value | 66,732 | ||
| Positive no. | 6 | ||
| Positive rate (%) | 4.7% | ||
| AMI | Median | 46,884 | |
| Positive no. | 28 | ||
| Positive rate (%) | 21.9% | ||
| p-value (vs. HD) | <0.0001 | ||
| DM | Median | 50,092 | |
| Positive no. | 27 | ||
| Positive rate (%) | 21.1% | ||
| p-value (vs. HD) | <0.0001 | ||
The upper panel provides details of participants, including the total numbers of collected samples, and the numbers of samples collected from male and female participants and their age distributions (median ± SD). The lower panel summarizes the results of s-JMJD6-Abs with purified JMJD6 protein. Positive antibody levels were determined using cutoff values set at the 95th percentile value of the HDs. The Kruskal–Wallis test and Bonferroni correction were employed for p-value calculation and multiple comparisons. SD, standard deviation. no., number. vs., versus. p-values of <0.05 and positive rate of >10% are marked in bold.