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Antibody responses and isotype distribution of virus-specific IgG in 6-week-old mice i.m. immunized with inactivated PR8 virus. Six-week-old mice (n = 4) were immunized intramuscularly with formalin-inactivated PR8 virus (10 μg/mouse) on day 0 and boosted on day 15. Serum samples were collected 10 days after boosting. Con, control, unimmunized CD4+ T-cell-deficient mice. Boost, serum samples after boost.
