Table 8.

Cardiovascular effects of Leonurus cardiaca L. (motherwort), Lamiaceae family—in vitro studies.

Herbal Raw Material	Active Compounds	Functions	Mechanism of Action	Model	Dose	References
Fruits	Stachydrine	Vasoprotective	↑ expression of PTCH1 and DHFR	isolated rat thoracic aortas, mesenteric arteries, and renal arteries from male Sprague–Dawley rats; bovine aorta endothelial cells (BAECs)	10 μM for 12 h; 0–10 μM for 24 h	[75]
Herb	Chlorogenic acid, orientin, quercetin, hyperoside, and rutin	Cardioprotective	↓ mitochondrial ROS generation	rat heart mitochondria	6.8 μg/mL 18.2 μg/mL	[78]

↑—increased, ↓—decreased.