Table 1.
Overview of the synthesized co-polymers with different feed ratios of functional monomer (HEAacr and Cys), ranging from 1% to 5%. Percentage following the name indicates the feed ratio of the corresponding functional monomer. Yield represents the overall yield of the polymer synthesis starting from the monomers and includes the post-polymerization modification. Incorporation ratio in the polymer chain was calculated using NMR and Ellman’s method for Cys. Molecular weight (Mw) and dispersity (Đ) were measured using SEC. * Spill during transfer to dialysis membrane. ** Solubility too low to obtain reliable results.
| Name | Yield | HEA (NMR) |
HEAacr (NMR) |
Mw (×103 g/mol) |
Đ | Name | Yield | Cys (NMR) |
Ellman’s Method |
Mw (×103 g/mol) |
Đ |
|---|---|---|---|---|---|---|---|---|---|---|---|
| HEAacr 1% | 44% | 0.88% | 0.67% | 11.4 | 1.43 | Cys 1% | 46% | 0.95% | 0.74% | 11.5 | 1.37 |
| HEAacr 2% | 43% | 1.8% | 1.8% | 28.0 | 1.89 | Cys 2% | 65% | 1.9% | 1.8% | 19.3 | 1.51 |
| HEAacr 3% | 46% | 2.7% | 2.8% | 46.8 | 2.19 | Cys 3% | 49% | 3.0% | 2.6% | 23.5 | 1.62 |
| HEAacr 4% | 77% | 3.8% | 3.3% | 127 ** | 4.99 ** | Cys 4% | 29% * | 3.8% | 3.9% | 18.0 | 1.58 |
| HEAacr 5% | 66% | ** | ** | ** | ** | Cys 5% | 57% | 4.7% | 4.3% | 28.3 | 1.55 |