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pH dependency of cell fusion. CHO cell lines expressing either or both of the chimeric E1 and E2 proteins (CHOE1, CHOE2, and CHOE1E2, respectively) and the parent cell line (CHO) were cocultured with Hep G2 cells. Cell fusion activity was determined after low-pH treatment (open bars) or without the treatment (solid bars). Cell fusion activity was determined as described for Fig. 2. RLU, relative light units.
