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Mutations created at the catalytic site and around the cleavage site
| Mutation | Catalytic site Around cleavage sitea |
|---|---|
| ↓ | |
| None (WT) | C1152R1299-G1300-G1301-G1302 |
| C1152S | S |
| R1299A | A |
| G1300A | A |
| G1301A | A |
| G1301S | S |
Cleavage occurs after G1301, as indicated by the vertical arrow.
