Comparison 2. Opioid versus control.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Pain (4 to 8 hours)	3	425	Mean Difference (IV, Fixed, 95% CI)	‐2.51 [‐3.02, ‐2.01]
2 Pain (9 to 24 hours)	3	425	Mean Difference (IV, Fixed, 95% CI)	‐0.32 [‐0.44, ‐0.20]
3 Pain (4 to 8 hours) (sensitivity analysis)	1	306	Mean Difference (IV, Fixed, 95% CI)	‐2.56 [‐3.07, ‐2.05]
4 Pain (9 to 24 hours) (sensitivity analysis)	1	306	Mean Difference (IV, Fixed, 95% CI)	‐0.32 [‐0.44, ‐0.20]