Figure 3. Serum Cytokine (N = 123) (A) and Inflammatory Laboratory (N = 270) (B) Levels (Estimated Marginal Means) Over Time Compared Between Those With and Without Any Neurologic Symptom at 18 Months.

Neurologic symptoms included headache, myalgia, anosmia, dysgeusia, numbness/tingling, dizziness, lightheadedness, cognitive, fainting, seizure, imbalance, speech, tremor, fatigue, sleep disorder, anxiety, depression. The dark green line represents patients with any neurologic symptom at 18 months, and the blue line represents those without a neurologic symptom at 18 months (with error bars). All cytokine and inflammatory laboratory levels significantly declined over time (all Friedman p < 0.001).