Table 1. Characteristics of individuals from the ADRC cohort, stratified by Area Deprivation Index group (low=ADI<50 corresponding to less deprived than the national average), (high=ADI ≥50 corresponding to more deprived than the national average).
| Sample characteristic n (%) or mean [SD] | Total (n=159) | Low ADI (n=116) | High ADI (n=43) | |||
| ADI1 | 36.7 | [25.6] | 24.1 | [15.5] | 70.5 | [14.1] |
| Demographics | ||||||
| Race | ||||||
| White | 142 | (89.3) | 111 | (95.7) | 31 | (72.1) |
| Black | 17 | (10.7) | 5 | (4.3) | 12 | (27.9) |
| Sex | ||||||
| Male | 89 | (56.0) | 63 | (54.3) | 26 | (60.5) |
| Female | 70 | (44.0) | 53 | (45.7) | 17 | (39.5) |
| Age at death | 76.6 | [10.0] | 76.6 | [9.6] | 76.6 | [11.1] |
| Education attainment | ||||||
| High school or less | 36 | (22.6) | 24 | (20.7) | 12 | (27.9) |
| College degree | 76 | (47.8) | 56 | (48.3) | 20 | (46.5) |
| Graduate degree | 47 | (29.6) | 36 | (31.0) | 11 | (25.6) |
| Clinical variables | ||||||
| Braak Stage | ||||||
| Stage 1 | 16 | (10.1) | 11 | (9.5) | 5 | (11.6) |
| Stage 2 | 11 | (6.9) | 6 | (5.2) | 5 | (11.6) |
| Stage 3 | 20 | (12.6) | 17 | (14.7) | 3 | (7.0) |
| Stage 4 | 17 | (10.7) | 12 | (10.3) | 5 | (11.6) |
| Stage 5 | 22 | (13.8) | 18 | (15.5) | 4 | (9.3) |
| Stage 6 | 73 | (45.9) | 52 | (44.8) | 21 | (48.8) |
| CERAD2 | ||||||
| No | 35 | (22.0) | 26 | (22.4) | 9 | (20.9) |
| Sparse | 4 | (2.5) | 4 | (3.4) | 0 | (0.0) |
| Moderate | 10 | (6.3) | 7 | (6.0) | 3 | (7.0) |
| Frequent | 110 | (69.2) | 79 | (68.1) | 31 | (72.1) |
| ABC3 | ||||||
| Not | 15 | (9.4) | 10 | (8.6) | 5 | (11.6) |
| Low | 29 | (18.2) | 21 | (18.1) | 8 | (18.6) |
| Intermediate | 22 | (13.8) | 17 | (14.7) | 5 | (11.6) |
| High | 93 | (58.5) | 68 | (58.6) | 25 | (58.1) |
| APOE4 ε4 Allele(s) | ||||||
| 0 | 70 | (44.0) | 51 | (44.0) | 19 | (44.2) |
| 1 | 68 | (42.8) | 53 | (45.7) | 15 | (34.9) |
| 2 | 21 | (13.2) | 12 | (10.3) | 9 | (20.9) |
| Cognitive classification | ||||||
| No dementia | 7 | (4.4) | 3 | (2.6) | 4 | (9.3) |
| Other dementia | 66 | (41.5) | 51 | (44.0) | 15 | (34.9) |
| AD5 | 86 | (54.2) | 62 | (53.4) | 24 | (55.8) |
1Area Deprivation Index; 2Consortium to establish a register for AD; 3Amyloid, Braak and CERAD; 4Apolipoprotein E; 5Alzheimer’s disease.