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. 2024 May 10;14(2):e140–e144. doi: 10.1055/a-2299-4026

Table 1. Summary of recommendations regarding use of systemic thrombolysis or catheter-guided techniques in pregnancy.

Organization Year Systemic thrombolysis Cather-guided techniques
American College of Obstetricians and Gynecologists (ACOG) 7 2018 Thrombolysis indicated for life-threatening or limb-threatening thromboembolism No discussion
American College of Chest Physicians (ACCP) 8 2012 Thrombolytic therapy is best reserved for life-threatening maternal thromboembolism No discussion
American Society of Hematology (ASH) 9 2018 If patient has acute pulmonary embolism (PE) and life-threatening hemodynamic instability, administer systemic thrombolysis alongside anticoagulant therapy More data is required on the effectiveness of catheter-directed thrombolysis in the pregnant population, including patients with limb-threatening ischemia
European Society of Cardiology (ESC) 10 2018 Thrombolysis only in patients with severe hypotension or shock No discussion
Royal College of Obstetricians and Gynaecologists (RCOG) 11 2015 Patients in shock should be assessed by a multidisciplinary team including the on-call consultant obstetrician and managed on an individual basis regarding intravenous (IV) unfractionated heparin, thrombolytic therapy, or thoracotomy and surgical embolectomy No discussion