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. 2023 Nov 22;61(6):3343–3356. doi: 10.1007/s12035-023-03791-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — miR-29a sponge attenuates amyloid deposition and decreases activated astrocytes and microglia in the hippocampus of 5×FAD mice and WT mice. A–C Representative immunofluorescence images. D–F Quantification of Aβ, GFAP, and Iba1 immunoreactivity. Data were analyzed via two-way ANOVA (genotype by group) with Sidak’s post hoc tests. Bars indicate mean ± SD. N = 3 per group. Scale bars represent 100 μm; *p < 0.05, **p < 0.01, compared with the control group