Table 1.
IC patient demographics and symptom scores based on presence of Hunner’s lesions
| All samples | NHIC | UIC | p-value | |
|---|---|---|---|---|
| Total | 493 | 372 | 119 | |
| Av Age (range) | 50.29 (20-92) | 47.78 (20-87) | 52.65 (25-84) | 0.011 |
| Av Years since Dx (range) | 10.31 (9.44) | 8.23 (0-42) | 14.83 (0-45) | < 0.001 |
| Gender | ||||
| Female | 473 (96.3%) | 358 (96.2%) | 115 (96.6%) | 0.724 |
| Male | 16 (3.3%) | 12 (3.2%) | 4 (3.4%) | |
| Co-morbidities | N = 294 (59.6%) | N = 209 (56.2%) | N = 83 (69.7%) | 0.010 |
| More than one | 154 (52.4%) | 108 (51.7%) | 44 (53.0%) | 0.106 |
| Female | 287 (60.8%) | 204 (57%) | 83 (72.2%) | 0.004 |
| Male | 5 (25%) | 4 (33.3%) | 0 | 0.182 |
| Types of co-morbidities | ||||
| IBS | 61 (12.4%) | 37 (9.9%) | 24 (20.2%) | 0.003 |
| Migraines | 127 (25.8%) | 89 (23.9%) | 37 (31.1%) | 0.119 |
| Kidney Stones | 52 (10.5%) | 34 (9.1%) | 17 (14.3%) | 0.109 |
| Fibromyalgia | 71 (15%) | 48 (13.4%) | 23 (20%) | 0.085 |
| Vulvodynia | 94 (19.9%) | 71 (19.8%) | 23 (20%) | 0.969 |
| Endometriosis | 107 (22.6%) | 75 (20.9%) | 32 (27.8%) | 0.125 |
| Lifestyle modifications | N = 455 (92.3%) | N = 335 (90.1%) | N = 108 (90.8%) | 0.822 |
| Medication | 287 (63.1%) | 212 (63.3%) | 73 (67.6%) | 0.402 |
| Diet | 319 (70.1%) | 245 (73.1%) | 73 (67.6%) | 0.369 |
| Instillation | 56 (12.3%) | 48 (14.3%) | 17 (15.7%) | 0.699 |
| PFPT | 98 (21.5%) | 75 (22.4%) | 23 (21.3%) | 0.843 |
| Questionnaire scores | N = 488 | N = 371 | N = 117 | |
| ICSI | 16.7 (5.66) | 11.75 (4.32) | 14.14 (4.47) | < 0.001 |
| ICPI | 10.7 (3.6) | 10.13 (3.48) | 11.56 (3.57) | 0.002 |
| OABq SF Symptom bother | 46.44 (21.71) | 43.07 (20.87) | 52.5 (22.22) | < 0.001 |
| OABq SF QoL | 55.97 (26.52) | 53.65 (25.71) | 63.26 (27.99) | < 0.001 |
| VAS | 5.38 (2.077) | 5.28 (2.087) | 5.70 (2.023) | 0.055 |
| Cytokine Levels | ||||
| GRO | 40.81 (76.67) | 34.77 (54.75) | 57.65 (120.14) | 0.102 |
| IL-6 | 1.34 (4.2) | 0.972 (2.46) | 2.39 (7.25) | 0.089 |
| IL-8 | 45.0 (210.77) | 34.03 (99.89) | 77.18 (395.95) | 0.337 |
| MCP-1 | 426.83 (537.42) | 388.3 (498.92) | 546.5 (636.47) | 0.044 |
Statistically significant p-values are bolded.