Table 3.
Association between urinary cytokine levels and symptom severity
| None | Moderate | Severe | p-value | |
|---|---|---|---|---|
| Urgency | N = 27 | N = 214 | N = 101 | |
| GRO | 23.67 (33.28) | 32.37 (46.44) | 62.63 (120.28) | 0.002 |
| IL-6 | 0.35 (0.49) | 0.88 (1.56) | 2.41 (7.06) | 0.031 |
| IL-8 | 10.67 (27.49) | 31.1 (95.37) | 83.3 (360.75) | 0.083 |
| MCP-1 | 239.9 (190.79) | 438.75 (595.97) | 454.32 (458.79) | 0.163 |
| Nocturia | N = 24 | N = 188 | N = 124 | |
| GRO | 32.32 (60.1) | 30.21 (44.2) | 55.66 (106.81) | 0.012 |
| IL-6 | 0.90 (1.24) | 0.85 (2.26) | 2.08 (6.11) | 0.029 |
| IL-8 | 55.54 (146.65) | 25.53 (68.13) | 72.07 (333.13) | 0.162 |
| MCP-1 | 456.71 (505.47) | 406.92 (545.9) | 460.89 (544.05) | 0.670 |
| Frequency | N = 133 | N = 131 | N = 30 | |
| GRO | 33.85 (55.38) | 40.31 (61.08) | 79.77 (175.85) | 0.015 |
| IL-6 | 0.75 (1.5) | 1.52 (3.57) | 3.32 (10.6) | 0.01 |
| IL-8 | 27.34 (77.0) | 41.9 (111.13) | 45.50 (111.38) | 0.403 |
| MCP-1 | 445.84 (617.67) | 441.91 (508.9) | 444.77 (507.30) | 0.998 |
Values are average cytokine levels in pg/ml with standard deviations. Statistical analysis performed using one-way ANOVA. Statistically significant p-values are bolded.