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. 2024 May 10;14:10726. doi: 10.1038/s41598-024-61615-0

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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DGPRI is an independent risk factor for postoperative recurrence of AFPNHCC. (a–c) LASSO-COX feature screening process and correlation coefficient. (d) Multivariate Cox regression forest plot for postoperative recurrence of AFPNHCC. (e) Kaplan–Meier survival analysis shows that high DGPRI is associated with earlier postoperative recurrence in AFPNHCC. (f) Time-dependent AUC results showed that DGPRI can better predict recurrence than GPRI and DBIL at 1–5 years postoperatively. DGPRI DBIL-GPR index, AFPNHCC alpha-fetoprotein-negative hepatocellular carcinoma, MVI microvascular invasion, DBIL direct bilirubin, GPRI gamma-glutamyl transpeptidase to platelet ratio index, AUC area under curve.