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In-vitro analysis of NMR and RTV penetration into three different human brain cells. (a) Evaluation of NMR uptake by cells in the absence or presence of RTV and (b) intracellular RTV uptake in the absence or presence of NMR. The p-values (*) indicate, * = < 0.05, *** = < 0.0002 and **** = < 0.0001. NMR nirmatrelvir, RTV ritonavir.
