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. 2024 May 10;15:3916. doi: 10.1038/s41467-024-47929-7

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — emm1 isolates are shown as proportions of the total number of isolates from iGAS cases submitted to and genotyped at the national reference laboratory for each quarter of each year. A adults ( ≥ 15 years); B children <15 years. The total number of isolates from iGAS cases received by the reference laboratory and genotyped in each quarter are shown on top of each bar; emm1 proportions are shown in navy blue. Pink shaded region highlights the period of COVID-19 non pharmaceutical interventions. Q1, January-March; Q2, April-June; Q3, July- September; Q4, October-December. Statistical analysis applied to 2022-2023: one-tailed proportion test of emm1 from Q1 2022 to Q3 2023 (p-values indicated in the figure). Source data are provided as a Source Data file Fig. 2.