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Requirements of terminal GUUU sequences for TLR7 activation. (A) Sequences of the indicated sncRNAs. (B and C) The indicated RNAs were subjected to DOTAP-mediated transfection into HMDMs. Total RNAs from the cells were subjected to RT-qPCR for the indicated mRNAs (B) or culture medium was subjected to measurement of concentration of the indicated cytokines (C).
