Fig. 9.

ImmTAB-inhA redirects PBMC to inhibit the viability of intracellular Mtb. Reduction of Mtb CFUs in three different experimental coculture conditions: (A) 2 × 10⁵ PBMC, 2.5 nM ImmTAB-inhA, 24 h incubation (n = 28); (B) 1 × 10⁶ PBMC, 2.5 nM ImmTAB-inhA, 48 h incubation (n = 12); (C) 5 × 10⁵ PBMC, 5 nM ImmTAB-inhA, 48 h incubation (n = 33). Responses from IGRA positive donors are shown in red. Paired t- test was used to assess whether the differences between experimental conditions were statistically significant.