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. 2024 May 3;79:100368. doi: 10.1016/j.clinsp.2024.100368

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© 2024 HCFMUSP. Published by Elsevier España, S.L.U.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 2 — Morphological and ultrastructural changes and increased apoptosis in cardiomyocytes caused by CIH. (A) Comparison of myocardial TEM images of rats in the CIH and NC groups. (B) Comparison of myocardial HE-staining images of rats in the CIH and NC groups. (C) TUNEL staining showed that the apoptotic rate of cardiomyocytes in rats with CIH significantly increased. (D) mRNA and protein expression levels of apoptosis-related protein caspase-3 significantly increased in the CIH group (*p < 0.05).