Table 3.
NAT2 haplotype distribution.
| Haplotype | Phenotype |
Allele frequency |
P value | |
|---|---|---|---|---|
|
T2D patients n (%) |
Healthy group n (%) |
|||
| 34 | 30 | |||
| NAT2*4 | Rapid | 11 (32.3) | 6 (20) | 0.8995 |
| NAT2*12 | 5 (14.7) | 2 (6.7) | ||
| NAT2*13 | 3 (8.8) | 1 (3.3) | ||
| NAT2*5 | Slow | 4 (11.8) | 10 (33.3) | 0.2975 |
| NAT2*6 | 3 (8.8) | 5 (16.7) | ||
| NAT2*7 | 8 (23.6) | 6 (20) | ||
| Haplotype | ||||
| Rapid | 19 (55.9) | 9 (30) | 0.0463* | |
| Slow | 15 (44.1) | 21 (70) | ||
| Phenotype | Phenotype frequency | |||
| 17 | 15 | |||
| Rapid | 6 (35.3) | 2 (13.3) | 0.1690 | |
| Intermediate | 7 (41.2) | 5 (33.3) | ||
| Slow | 4 (23.5) | 8 (53.3) | ||
All the values are represented as n (%); d.f. = 1 for all tests. P value < 0.05 was taken as significant.