Fig. 5.

The ultrasound at 32 weeks 6 days of Case 2. a) The profile view showed an absent nasal bone. The cerebral structures (arrow) below the skull was supposed to be obscured by the acoustic shadow, but is clearly identified; b) The cerebral structures (arrow) below the skull was supposed to be obscured by the acoustic shadow, but is clearly identified; c) Skull deformation upon light pressure (arrows), all suggestive of poor cranial ossification; d) Absent nasal bones (arrow) on 3D skeletal views; e) Bilateral hypoplastic clavicles (arrows), stiff and short when compared with normal ones; f) Normal clavicles in a fetus at 32 weeks 2 days.