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. 2024 May 10;29:68. doi: 10.1186/s11658-024-00580-y

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — NLRP4E knockdown disrupted actin cap formation. A, B Phalloidin staining and quantification show that NLRP4E knockdown caused a significant decrease in the intensity of actin filaments at the cap region. DNA is shown in blue, and phalloidin in red. C, D Immunofluorescence analysis shows that NLRP4E knockdown caused a significant decrease in the intensity of ARP3 at the cap region. DNA is shown in blue and ARP3 in green. Scale bar, 20 μm. * indicates p < 0.05; **** indicates p < 0.0001