Overview of the tumor suppressor TP53 in HCC. (A) RNA expression of TP53 in various normal tissues. (B) Relative TP53 expression in normal and tumor tissues of HCC patients. (C) TP53 expression in different tumor stages. (D) TP53 expression in different degrees of tumor differentiation. (E) Frequency of genetic alterations with TP53 in HCC from cBioPortal. (F) TP53 expression in different copy-number alterations of TP53. (G) Correlation between expression and copy-number values of TP53. Prognostic analysis between TP53 mutated and wild type groups, including OS (H), DFS (I), DSS (J), and PFS (K). HCC, Hepatocellular carcinoma; OS, Overall survival; DFS, Disease Free survival; DSS, Disease-specific survival; PFS, Progression Free survival.