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. 2024 Apr 30;10(9):e30066. doi: 10.1016/j.heliyon.2024.e30066

Fig. 5.

Fig. 5

Construction and correlation analysis of the ceRNA network. (A) The subcellular localization of the 4 lncRNAs (ALMS1-IT1, BPESC1, LINC00491 and TCL6) predicted by lncLocator. (B) Correlation between the expression of hsa-miR-139-5p and the 4 lncRNAs. (C) Correlation between the expression of MEX3A and the 4 lncRNAs. (D) Correlation between the expression of hsa-miR-139-5p and MEX3A. (E) Schematic model of the ceRNA network. Red represents up-regulated and blue represents down-regulated. (F) Base pairing between LINC00491, TCL6 and hsa-miR-139-5p predicted by miRcode, hsa-miR-139-5p and MEX3A predicted by Targetscan. (G) Luciferase activities of wild type (WT) and mutated (Mut) LINC00491, TCL6 and MEX3A reporter plasmid in HEPG2 cells co-transfected with miR-139-5p mimic.