Table 2.

Ocular findings for familial hypercholesterolemia patients and controls with multivariate logistic regression.

	Control (n = 28)		Patients General (n = 28)		p-value	Odds Ratio (95 % CI)		Adjusted Odds Ratio (95 % CI)
Corneal arcus	1	(4)	18	(64)	<0.001*	48.6	(5.7–413.2)	83.1	(8.9–776.5)
Lipid deposits or xanthelasmas	0	(0)	9	(32)	0.001*
Excision of xanthomas	0	(0)	8	(29)	0.004*
TBUT <10 s	11	(42)	12	43	1.0	1.0	(0.4–3.0)	1.1	(0.4–3.6)
Occluded retinal arteries	0	(0)	1	(4)	0.31
Retinal arterial plaque	0	(0)	2	(7)	0.15
Retinal venous plaque	0	(0)	2	(7)	0.15
Retinal arteriosclerosis	4	(14)	18	(64)	<0.001*	10.8	(2.9–40.1)	6.8	(1.6–27.8)
Grade 1	4	(14)	12	(43)
Grade 2	0	(0)	6	(21)

CI = confidence interval.

LDL = low-density lipoprotein.

TBUT = tear break-up time.

Data are in n (%) unless otherwise indicated.