Table 3.

Multiple linear regression models for the causal steps mediation approach.

	Model 1: stress		Model 2: psychological		Model 3: psychological		Model 4: physical		Model 5: Physical
Characteristic	Beta (95% CI)	p	Beta (95% CI)	p	Beta (95% CI)	p	Beta (95% CI)	p	Beta (95% CI)	p
Perceived stress	-	-	-	-	−0.23 (−0.24, −0.22)	<0.0001	-		−0.11 (−0.12, −0.10)	<0.0001
Weight-related discrimination	3.62 (3.06, 4.17)	<0.0001	−1.11 (−1.35, −0.87)	<0.00001	−0.29 (−0.50, −0.08)	0.007	−0.63 (−0.83, −0.43)	<0.0001	−0.22 (−0.41, −0.02)	0.028
Adjusted $R^2$	21.18%		23.35%		45.14%		23.75%		31.57%
Model significance	$F_{\mathrm{15,5088}}$ =100.8, p < 0.0001		$F_{15, 5088}$ = 108.8, p < 0.0001		$F_{16, 5087}$ = 270.4, p < 0.0001		$F_{15, 5088}$ = 112.1, p < 0.0001		$F_{16, 5087}$ = 152.9, p < 0.0001

Model 1 tests the effect of weight-related discrimination (independent variable) on perceived stress (mediator); Model 2 tests the direct effect of weight-related discrimination on psychological wellbeing (outcome variable); Model 3 tests the effect of perceived stress on psychological wellbeing while adjusting for weight-related discrimination; Model 4 tests the direct effects of weight-related discrimination on physical wellbeing (outcome variable); Model 5 tests the effects of perceived stress on physical wellbeing while adjusting for weight-related discrimination. All five models were adjusted for age, body mass index, sex at birth, marital status, race and ethnicity, household income, and education. The full linear regression model, showing the effects of covariates, is in supplementary table S2.

CI: Confidence Interval.