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. 2024 May 11;20(3):54. doi: 10.1007/s11306-024-02127-w

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A schematic summary of the metabolic changes associated with poorly controlled type 2 diabetes in this metabolomics investigation. The directional changes in the concentrations of the metabolite markers are shown to increase (↑) or decrease (↓) relative to the healthy control group. FAD flavin adenine dinucleotide, FADH flavin adenine dinucleotide + hydrogen, NAD nicotinamide adenine dinucleotide, NADH nicotinamide adenine dinucleotide + hydrogen, ATP adenosine triphosphate, ADP adenosine diphosphate