Table 3.
Factor loadings showing the strength of relationship between factors and individual biomarkers (n = 95).
| Biomarker | Factor Loadings for Brain Injury Biomarkers | ||
|---|---|---|---|
| 1 | 2 | 3 | |
| GFAP | 0.76 | − 0.02 | 0.08 |
| S100β | 0.61 | 0.05 | − 0.09 |
| MCP1 | 0.58 | 0.01 | − 0.16 |
| VILIP-1 | 0.57 | 0.09 | − 0.24 |
| NSE | 0.54 | 0.18 | − 0.08 |
| BDNF | 0.45 | − 0.06 | 0.53 |
| NRGN | 0.30 | 0.27 | 0.24 |
| vWF | 0.02 | 0.63 | 0.01 |
| PDGFRβ | 0.01 | 0.53 | 0.02 |
| NPTX1 | − 0.01 | 0.73 | 0.01 |
| MMP-9 | − 0.14 | 0.03 | 0.83 |
| Variance explained, % | 21 | 13 | 10 |
| Cumulative variance | 21 | 34 | 44 |
BDNF, brain-derived neurotrophic factor; GFAP, glial fibrillary acidic protein; MCP1, monocyte chemoattractant protein 1; MMP-9, matrix metalloproteinase 9; NRGN, neurogranin, NPTX1, neuronal pentraxin 1; NSE, neuron-specific enolase; PDGFRβ, platelet-derived growth factor receptor beta; VILIP-1, visinin-like protein 1, vWF, von Willebrand factor.
Bold indicates salient factors using criterion of factor loadings ≥ 0.3.