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Acute liraglutide administration attenuated nicotine self-administration in male and female rats. Total active lever responses (A & C) and nicotine infusions (B & D) were significantly reduced in both male and female rats treated with 25 μg/kg liraglutide versus vehicle-treated controls on their final day of nicotine self-administration. (males: n=9/treatment; females: n=11 vehicle, n=13 liraglutide; * p<0.05,** p<0.01, Bonferroni or un-paired t-test).
