Table 2.

Clinical outcomes included in the systematic review and their corresponding definition/measure of the outcome

Outcome	Definition/measure of outcome
ADRs	UKU adverse effects score26,27
Symptom severity	SAPS26 PANSS27 CGI-S17,21 Children’s Global Assessment Scale (CGAS)21
Clinicians’ opinions	PIP-FQ25
Hospitalizations	Overall hospitalization stays per patient23
Medication prescribing	Antipsychotic drug persistence, measured as time in days to the first modification of the initial antipsychotic treatment (drug or dose change), to indicate tolerability of medication26 Drug changes26 Dose changes by visual inspection of temporal dose-adjustment graphs26 Mean daily dose22 Polytherapy through the number of antipsychotics prescribed22