Table 2.

Mendelian Randomization assessments regarding the connection between genetically instrumented immune cells and GBM.

Outcome	Exposure	Method	OR	95% CI	P-value
GBM	CD45 on CD33+ HLA DR+ CD14dim	MR Egger	1.263	(0.936–1.703)	0.150
		Weighted median	1.359	(1.013–1.823)	0.041
		IVW	1.307	(1.072–1.595)	0.008
		Simple mode	1.216	(0.767–1.927)	0.420
		Weighted mode	1.331	(0.977–1.812)	0.091
		BWMR	1.344	(1.073–1.683)	0.010
GBM	CD33+ HLA DR+ absolute count	MR Egger	0.852	(0.762–0.953)	0.009
		Weighted median	0.869	(0.751–1.006)	0.060
		IVW	0.894	(0.815–0.981)	0.018
		Simple mode	0.981	(0.785–1.227)	0.868
		Weighted mode	0.900	(0.794–1.019)	0.107
		BWMR	0.880	(0.784–0.989)	0.032
GBM	IgD+ CD24+ B cell absolute count	MR Egger	1.377	(0.775–2.445)	0.288
		Weighted median	1.495	(0.945–2.366)	0.086
		IVW	1.357	(1.000–1.840)	0.050
		Simple mode	2.043	(0.987–4.229)	0.067
		Weighted mode	1.555	(0.922–2.634)	0.112
		BWMR	1.375	(0.966–1.957)	0.077