FIG. 5.

Kinetics of IFN-γ-producing cells in H-2^b/b and H-2^bm14/b mice after FV infection. Spleen cells from H-2^b/b or H-2^a/b mice were serially diluted, activated with stimulator cells, and analyzed for the number of IFN-γ-producing cells using an IFN-γ-specific ELISPOT assay as described for Fig. 2. The number of IFN-γ-producing spleen cells per spleen was determined by multiplying the number of IFN-γ-producing cells per 5 × 10⁵ cells by the number of total cells per spleen. Data are shown as the mean numbers of IFN-γ-producing cells per spleen ± the standard errors of the means for 3 to 10 mice per group.