Table 6:
Comparison of clinical characteristics at disease onset between remission and ineffective group.
| Clinical characteristics | Remission group (n = 11) | Ineffective group (n = 5) | P-value |
|---|---|---|---|
| Age, years, mean ± SD | 10.0 ± 2.6 | 11.3 ± 3.0 | .388 |
| Sex (female:male) | 9:2 | 3:2 | .547 |
| Duration of IgAVN before TAC, month, median (IQR) | 24 (9, 35) | 10 (4, 45) | .308 |
| IgA, g/L, mean ± SD | 1.98 ± 0.88 | 1.60 ± 1.13 | .486 |
| C3, g/L, mean ± SD | 0.89 ± 0.19 | 0.84 ± 0.30 | .671 |
| Urinary protein, mg/kg/day, median (IQR) | 76.8 (55.9, 160.8) | 69.7 (32.4, 248.8) | .913 |
| eGFR (n) | |||
| >90 mL/min/1.73 m2 | 11 | 5 | |
| <90 mL/min/1.73 m2 | 1 | 0 | .706 |
| SQC | 7.7 ± 1.7 | 9.6 ± 2.3 | .092 |
| Clinical manifestations (n) | |||
| Nephrotic syndrome | 7 | 3 | |
| Nephrotic syndrome and nephritis syndrome | 3 | 1 | |
| Nephritis syndrome | 0 | 1 | .643 |
| Haematuria and proteinuria | 1 | 0 | |
| ISKDC grade (n) | |||
| IIIa | 4 | 1 | |
| IIIb | 4 | 3 | .790 |
| IVb | 2 | 1 | |
| Tubulointerstitial injury grade (n) | |||
| Grade 1 (–) | 5 | 0 | |
| Grade 2 (+) | 4 | 2 | .096 |
| Grade 3 (++) | 1 | 3 |
IQR, interquartile range; SD, standard deviation.