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. Author manuscript; available in PMC: 2024 May 13.
Published in final edited form as: Mol Cell. 2023 Sep 7;83(17):3095–3107.e9. doi: 10.1016/j.molcel.2023.08.006

Figure 6. RNA and nucleolar proteins exhibit vastly different dynamics.

Figure 6.

(A) RNA labeled with tC nucleotides does not recover after bleaching of half of the GC, whereas NPM1-mCh exhibits full recovery.

(B) FRAP recovery curve for tC (black) and NPM1 (pink). Dotted line represents expectation for RNA recovery if the nucleolus were a simple liquid.

(C) NPM1 (pink), R-proteins (green), and RNA (EU in gray line, tC in black dots) have different dynamics. Shadded error regions are mean prediction bands.