Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
| aqueous
solubility (μM) |
|||||
|---|---|---|---|---|---|
| compound | pH 1.2 | pH 6.8 | PAMPA permeability (×10–6 cm/s) | hepatic microsome stability in rats (mL/min/kg) | plasma protein binding in rats (% unbound) |
| 4 | <0.02 | >100 | >50 | 171 | <0.01 |
| 5 | 0.054 | >100 | >50 | 237 | <0.01 |
| 6 | <0.01 | >100 | >50 | 275 | <0.01 |
| 7 | <0.02 | 89.5 | >50 | 123 | <0.01 |
| 8 | <0.01 | >100 | >50 | 296 | <0.01 |
| 1a | 0.088 | >100 | >50 | 38.7 | 0.51 |
