Table 2.
Clinical outcomes for abdominal surgery patients: Intravenous administration of acetaminophen vs no acetaminophen groups
| Outcome | Acetaminophen (n = 60) | No acetaminophen (n = 269) | P |
|---|---|---|---|
| LOS, days | 9.2 ± 4.8 | 9.1 ± 5.3 | .90 |
| Colon resection | 9.2 ± 5.5 | 9.1 ± 5.5 | – |
| Pancreaticoduodenectomy | 9.3 ± 3.7 | 9.4 ± 3.6 | – |
| ICU LOS, days | 2.1 ± 2.5 | 2.2 ± 3.0 | .91 |
| 24 hour opioid use, mg a | 142.2 ± 118.8 | 207.2 ± 184.7 | .02 |
| Total opioid use, mg | 724.1 ± 686.7 | 757.9 ± 717.4 | .75 |
| 24 hour pain scores, VAS | 2.0 ± 1.6 | 1.5 ± 1.3 | .007 |
| Total pain scores, VAS | 2.2 ± 1.0 | 1.5 ± 1.3 | <.001 |
| Time to rescue, hours | 5.5 ± 2.7 | 4.9 ± 2.9 | .21 |
| Time to BM, hours | 86.2 ± 53.3 | 87.5 ± 51.3 | .87 |
| Time to diet, hours | 157.9 ± 89.7 | 133.8 ± 98.1 | .46 |
| >4 g/day of acetaminophen, n (%) | 15 (20) | 2 (0.7) | <.001 |
Note: Values given as mean ± SD, unless otherwise indicated. BM = bowel movement; ICU = intensive care unit; LOS = length of stay; VAS = visual analog scale.
a
Opioid use = oral morphine equivalents