Fig. 3.

Volcano plot of the differential region expression between ccRCC and urolithiasis control patients. Each point stands for a tested region. Red dots indicate significant differences with a false discovery rate (FDR) < 0.05 adjusting for multiple testing. Horizontal axis shows strength and direction of the difference (positive values means higher expression in ccRCC compared to urolithiasis). Vertical axis shows the logarithmized p-value (higher values mean lower p-value). Genes that overlap with the significantly altered regions are annotated