Table 2.
Demographic and technical characteristics of the tumor-free control subjects with urolithiasis
| Discovery cohort (RNA-seq) | Validation cohort (qPCR) | ||||
|---|---|---|---|---|---|
| Parameter | Category | Number [n] | Percentage [%] | Number [n] | Percentage [%] |
| gender | male | 15 | 94 | 20 | 83 |
| female | 1 | 6 | 4 | 17 | |
| age (years) | median (range) | 63 (43–77) | 62 (43–77) | ||
| obesity (BMI ≥ 30) | yes | 3 | 19 | 4 | 17 |
| no | 13 | 81 | 20 | 83 | |
| hypertension | yes | 10 | 63 | 14 | 58 |
| no | 6 | 38 | 10 | 42 | |
| urine volume (ml) | median (range) | 58.5 (30–100) | 58.5 (30–100) | ||
| RNA yield (ng) | median (range) | 27 (14-1309) | 44 (14-3234) | ||
The control group included n = 16 patients with urolithiasis of 64 test subjects in the RNA-seq discovery cohort and n = 24 patients with urolithiasis of 78 test subjects in the qPCR validation cohort