Table 1.
Candidate indicators | Median “necessity” rating after rating round 2 | Accepted for the 3rd round |
---|---|---|
ADR: falls and fall-related injuries | ||
A. History of fall and prescribed one single antidepressant with sedating, anticholinergic, or orthostatic properties (TCA, mirtazapine, or trazodone) | 7 | Accepted |
B. History of fall and prescribed one single antidepressant with sedating, anticholinergic, or orthostatic properties (TCA, mirtazapine, or trazodone) with one further fall risk-increasing drug | 8 | Redundant |
C. History of fall and prescribed one single antidepressant with sedating, anticholinergic, or orthostatic properties (TCA, mirtazapine, or trazodone) with two or more further fall risk-increasing drugs | 9 | Redundant |
aMultiple variations of candidate indicators were rated in order to identify thresholds beyond which a critical review of antidepressant use was considered necessary. Candidate indicators B and C were found to be redundant after candidate indicator A was accepted (necessity rating of ≥ 7)