Table 2.

Univariable and multivariable analysis for predictors of overall survival in the overall cohort

	Univariate analysis			Multivariate analysis
	HR (95% CI)	P value		HR (95% CI)	P value
Age, years
≥ 65 vs. <65	1.070 (0.754–1.517)	0.424
Sex
Male vs. Female	1.056 (0.751–1.485)	0.827
Comorbidity
Yes vs. No	1.641 (1.137–2.367)	0.011		1.300 (0.944–1.791)	0.108
Surgical approach
Laparoscopic vs. Open	0.533 (0.278–1.023)	0.132
Gastrectomy extent
Total vs. Partial	1.499 (1.065–2.111)	0.001		1.286(0.954–1.735)	0.099
Tumor size, cm
≥ 5 vs. <5	1.760 (1.185–2.614)	< 0.001		1.091 (0.790–1.504)	0.600
Tumor differentiation
Undifferentiated vs. Differentiated	1.438 (0.977–2.118)	0.001		1.342 (0.960–1.875)	0.085
TNM stage
II vs. I	1.730 (1.130–2.646)	0.010		2.079 (1.410–3.067)	< 0.001
III vs. I	5.376 (2.353–12.195)	< 0.001		3.846 (1.626–5.882)	< 0.001
Adjuvant chemotherapy
Yes vs. No	0.827 (0.592–1.153)	0.329		0.731 (0.552–0.969)	0.030
ALI
Low vs. High	1.844 (1.314–2.586)	< 0.001		1.449 (1.028–2.045)	0.034
LMR
Low vs. High	1.648 (1.181–2.299)	0.009		1.161 (0.852–1.585)	0.343
PLR
Low vs. High	0.742 (0.525–1.048)	0.003		1.070 (0.749–1.526)	0.711

HR: hazard ratio; CI: confidence interval; ALI: advanced lung cancer inflammation index; PLR: platelet to lymphocyte ratio; LMR: lymphocyte to monocyte ratio