Fig. 7.

The preparation and in vivo assessments of osseointegration and anti-infection ability of Ti-PAA-NCl. a Schematic diagram of the synthesis of Ti-PAA-NCl coating on the Ti substrates. b Time period of experiments. c New bone formation via Van Gieson’s staining after 4 weeks of implantation (scale bar is 500 μm in the top image and 250 μm in the bottom one). d Micro-CT images of the bone height surrounding the implants after osseointegration for 4 weeks, peri-implantitis for 8 weeks, and re-osseointegration for 4 weeks (scale bars is 500 μm). e Micro-CT three-dimensional reconstructions of the implants and surrounding bone tissues (scale bars is 500 μm) [105]. Copyright 2021, the author(s). Ti titanium, N-Cl nitrogen-halamine, Ti-OH alkali-heated titanium disks, Ti-PAA-Cl polymeric coating loaded with chloramine