Table 8.
Clinical applications regarding biomaterials and surface modification strategies for dental peri-implantitis management
| Materials | Sample quality | Setting area | Subjects | Follow-up | Main result | References |
|---|---|---|---|---|---|---|
| Anatase TiO2 coating on Ti6Al4V discs | 48 (8 C/16T) | Oral cavity | 8 (3 M/5F), between 20 and 25 years | 24 h | Inhibit bacterial attachment and biofilm formation | [129] |
| Coating the internal part of the Ti dental implant with chlorhexidine gluconate | 60 (30 C/30T) | Oral cavity (implants were placed 2 mm under the crestal bone level) | 15 (6 M/9F), between 45 and 61 years | 6 months | No adverse effects, implant failure, or local inflammation were observed, all experimental sites showed good soft tissue healing | [139] |
| N-halamine polymeric-coated Ti disks | 44 (22 C/22T) | Oral cavity (middle-third of buccal surfaces of upper and lower first molars) | 11 | 4 or 12 weeks | Inhibit biofilm formation, the antibacterial property can be further enhanced by rechlorination | [105] |
TiO2 titanium dioxide, Ti titanium, C control, T test, M male, F female