Relative changes in overall (top) and diurnal (bottom) glycemic metrics for URLi with original therapy parameters, URLi + increase in MB (↑ MB), URLi + increase in BR (↑ BR), and URLi + increase in both MB and BR (↑ MB, BR) with respect to lispro with original therapy parameters. Abbreviations: URLi, ultra-rapid lispro; MB, meal bolus; BR, basal rate; TIR, time in range; TBR, time below range.