TABLE 1.
Genome-to-PFU ratios for chimeric Ad vectorsa
| Virus | Genomes/ml (1012) | PFU/ml | Genome/PFU ratio |
|---|---|---|---|
| Ad5L | 2.2 | 1.39 × 1011 | 13 ± 4.2 |
| Ad5S | 1.46 | 1.04 × 1010 | 140 ± 54 |
| Ad5/9L | 1.73 | 6.05 × 1010 | 29 ± 6 |
| Ad5/9S | 1.28 | 2.2 × 109 | 582 ± 158 |
| Ad5/35L | 1.6 | 1.16 × 1011 | 14 ± 4.8 |
| Ad5/35S | 1.98 | 1.18 × 1011 | 17 ± 6 |
The genome titers of preparations of purified Ad vectors were measured by quantitative Southern blot analysis (61). The plaque titers were determined on 293 cells under the conditions described in Materials and Methods.