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. 2000 Nov;74(22):10274–10286. doi: 10.1128/jvi.74.22.10274-10286.2000

TABLE 1.

Genome-to-PFU ratios for chimeric Ad vectorsa

Virus Genomes/ml (1012) PFU/ml Genome/PFU ratio
Ad5L 2.2 1.39 × 1011 13 ± 4.2
Ad5S 1.46 1.04 × 1010 140 ± 54
Ad5/9L 1.73 6.05 × 1010 29 ± 6
Ad5/9S 1.28 2.2 × 109 582 ± 158
Ad5/35L 1.6 1.16 × 1011 14 ± 4.8
Ad5/35S 1.98 1.18 × 1011 17 ± 6
a

The genome titers of preparations of purified Ad vectors were measured by quantitative Southern blot analysis (61). The plaque titers were determined on 293 cells under the conditions described in Materials and Methods.