Table 3.

For each sex and age category strata, an interrupted time series of weekly emergency medical service calls for mental health from January 2019 to July 2020, using negative binomial regression offset by the total population of subgroup, for regions in the United Kingdom and in Canada.^a

Strata and variable			East Midlands region, United Kingdom	Niagara and Hamilton regions, Canada
Sex
	Female
		Attendances, n	50,098	10,829
		Per week, IRRb (95% CI)	1.002 (1.002-1.003) c	0.999 (0.999-1.000)
		Lockdown, IRR (95% CI)	1.101 (1.007-1.203)	1.012 (0.856-1.196)
		Lockdown trend, IRR (95% CI)	0.998 (0.990-1.007)	0.992 (0.976-1.008)
	Male
		Attendances, n	36,515	8581
		Per week, IRR (95% CI)	1.002 (1.001-1.003)	0.999 (0.999-1.000)
		Lockdown, IRR (95% CI)	1.163 (1.050-1.288)	0.830 (0.702-0.980)
		Lockdown trend, IRR (95% CI)	0.998 (0.989-1.008)	1.017 (1.001-1.033)
Age
	<18 years
		Attendances, n	4239	1572
		Per week, IRR (95% CI)	1.003 (1.002-1.004)	0.999 (0.997-1.001)
		Lockdown, IRR (95% CI)	0.723 (0.579-0.913)	0.687 (0.451-1.038)
		Lockdown trend, IRR (95% CI)	1.021 (0.999-1.042)	1.024 (0.985-1.065)
	18-44 years
		Attendances, n	39,648	10,382
		Per week, IRR (95% CI)	1.003 (1.002-1.003)	1.000 (0.999-1.001)
		Lockdown, IRR (95% CI)	1.097 (0.986-1.220)	0.969 (0.824-1.139)
		Lockdown trend, IRR (95% CI)	0.994 (0.985-1.004)	0.997 (0.982-1.012)
	45-65 years
		Attendances, n	22,970	4764
		Per week, IRR (95% CI)	1.002 (1.001-1.002)	0.999 (0.998-1.001)
		Lockdown, IRR (95% CI)	1.255 (1.123-1.403)	0.905 (0.723-1.131)
		Lockdown trend, IRR (95% CI)	0.991 (0.981-1.002)	1.012 (0.991-1.012)
	>65 years
		Attendances, n	20,229	2692
		Per week, IRR (95% CI)	1.001 (1.000-1.002)	0.999 (0.997-1.000)
		Lockdown, IRR (95% CI)	1.118 (1.005-1.244)	0.938 (0.721-1.215)
		Lockdown trend, IRR (95% CI)	1.011 (1.001-1.021)	1.002 (0.978-1.027)

^aModels have been adjusted for seasonality (each month as a variable).

^bIRR: incidence rate ratio.

^cIRRs statistically significant at P<.05 are indicated in italics format.