Table 2.
For patients with cirrhosis and no prior variceal bleeding: NSBB or EVL (also see Figure 3)
| Therapy | No ascites | Ascites | Goal |
|---|---|---|---|
| Propranolol | 20–160 mg BID | 20–80 mg BID | Titrate to HR 55–60 or SBP <90 |
| Nadolol | 20–160 mg daily | 20–80 mg daily | Titrate to HR 55–60 or SBP <90 |
| Carvedilol | 3.125 – 12.5 mg daily | Avoid | Titrate to 12.5-25 mg/day or SBP<90 |
| EVL | EGD q 2–8 weeks until EV eradication → repeat EGD at 3–6 months → EGD q6–12 months if no large varices | Variceal eradication; if recurrent large varices → resume banding q2–8 weeks | |