| Ball et al./2018 |
USA, Italy |
Systematic Review |
PubMed |
FFRCT represents an exciting development in the evaluation of ischemic heart disease. Using advances in imaging and CFD, FFRCT offers a noninvasive diagnostic strategy to identify functionally significant lesions in order to distinguish between patients who can safely avoid ICA and those patients who require revascularization. |
| Ford et al./ 2020 |
UK |
Systematic Literature Review |
Google Scholar |
A personalized approach to invasive diagnostic testing permits a diagnosis to be made (or excluded) during the patients’ index presentation |
| Hoffmann et al./2017 |
US, Canada |
Ransomized Control Trial |
PubMed |
Coronary CTA, by identifying patients at risk because of nonobstructive CAD, provides better prognostic information than functional testing in contemporary patients who have stable chest pain with a low burden of obstructive CAD, myocardial ischemia, and events. |
| Morone et al./2022 |
Italy |
Systematic Review |
PubMed and Medline |
An up-to-date guide for the choice and the interpretation of the currently available noninvasive anatomical and/or functional tests, focusing on emerging techniques, which could provide deeper pathophysiological insights to refine diagnostic and therapeutic pathways in the next future. |
| Nakano et al./2022 |
Japan |
Systematic Review |
Google Scholar |
Current guidelines to manage stable coronary artery disease |
| Pontone et al./2019 |
Italy, Australia, Sweden |
Meta-analysis |
PubMed |
A negative coronary CT angiography has a higher test performance than other index tests to exclude clinically-important CAD. A positive stress myocardial CT perfusion added to coronary CT angiography, stress cardiac MR, and PET have a higher test performance to identify patients requiring invasive coronary artery evaluation. |
| Maron et al./2020 |
USA, UK, Spain, Canada, India, Poland Italy, Germany, Hungary, Japan, France, New Zealand, Russia |
Randomized Control Trial |
PubMed and Scopus |
Among patients with stable coronary disease and moderate or severe ischemia, we did not find evidence that an initial invasive strategy, as compared with an initial conservative strategy, reduced the risk of ischemic cardiovascular events or death from any cause over a median of 3.2 years. |
| Siontis et al./2018 |
Switzerland, Canada, UK, Greece |
Systematic Review |
Google Scholar |
For patients with low risk acute coronary syndrome, an initial diagnostic strategy of stress echocardiography or cardiovascular magnetic resonance is associated with fewer referrals for invasive coronary angiography and revascularisation procedures than non-invasive anatomical testing, without apparent impact on the future risk of myocardial infarction. |
| Rasmussen et al./2019 |
Denmark, UK |
Randomized Control Trial |
PubMed and Medline |
The results of the Dan-NICAD 2 study are expected to contribute to the improvement of diagnostic strategies for patients suspected of CAD in 3 different steps: risk stratification prior to coronary CTA, diagnostic strategy after coronary CTA, and invasive wireless QFR analysis as an alternative to ICA-FFR. |
