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. 2024 May 9;15:55–67. doi: 10.2147/LCTT.S455034

Figure 4.

Figure 4

Effect of antiretroviral and selinexor treatment on cell viability analyzed by Cell Counting Kit-8 assay. (A) Effect of 20 uM single selinexor or antiretroviral treatments on cell viability in the H520, PC9, A549 and H1975 lung cancer cell lines, compared to the control. (B) Effect of single and combined selinexor plus osimertinib or erlotinib treatment on cell viability in the H1975 cell line, using different concentrations of selinexor. (C) Effect of single and combined selinexor plus osimertinib or erlotinib treatment on cell viability in the PC9 cell line, using different concentrations of selinexor. (D) Effect of single and combined selinexor plus MEK-inhibition treatment on cell viability in the A549 cell line, using different concentrations of selinexor. (E) Effect of single and combined selinexor plus MEK-inhibition treatment on cell viability in the H460 cell line, using different concentrations of selinexor. Data were analyzed using unpaired t-test comparisons. *P <0.05, **P <0.01, compared to control. #P <0.05, ##P <0.01, comparison between two groups marked with horizontal lines.