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. 2024 May 13;19(5):e0303287. doi: 10.1371/journal.pone.0303287

Table 1. Summary of patient characteristics (demography, cardiovascular risk factors, primary preventive medication, and stroke characteristics) categorized by mRS.

Reported descriptive statistics including mean, standard deviation (SD), median, quartiles (Q1, Q3), and frequencies (number of patients) (%). The last column shows the proportion of missing cases in each of the variables (features).

Outcomes 3 months after stroke Missing (%)
All patients mRS 0–2 mRS 3–5 mRS 6
Number of patients (%) 102,135 (100) 43,361 (42.5) 36,687 (35.9) 22,087 (21.6)
Age (mean [SD]) 75.8 [12.0] 70.4 [11.6] 78.7 [10.8] 81.8 [10.3] -
Male (%) 54,473 (53.3) 26,797 (61.8) 17,328 (47.2) 10,348 (46.9) -
Atrial Fibrillation (%) 30,195 (29.6) 8,315 (19.2) 12,234 (33.3) 9,646 (43.7) 152 (0.2)
Diabetes (%) 22,355 (21.9) 7,759 (17.9) 9,358 (25.5) 5,238 (23.7) 214 (0.2)
Previous Stroke or TIA (%) 27,787 (27.2) 8,505 (19.6) 12,013 (32.7) 7,269 (32.9) 186 (0.2)
Smoking (%) 11,394 (11.2) 5,852 (13.5) 4,020 (11.0) 1,522 (6.9) 14,252 (14.0)
Blood pressure (BP) lowering medication (%) 65,004 (63.6) 24,938 (57.5) 25,076 (68.4) 14,990 (67.9) 395 (0.4)
Lipid-lowering drugs (%) 32,616 (31.9) 13,473 (31.1) 12,638 (34.4) 6,505 (29.5) 441 (0.4)
Prior anticoagulation (%) 15,824 (15.5) 4,526 (10.4) 6,423 (17.5) 4,875 (22.1) 318 (0.3)
Pre-stroke mRS (%) 5,199 (5.1)
0–2 (Reference) 69,795 (68.3) 41,484 (95.7) 19,977 (54.5) 8,334 (37.7)
3 14,772 (14.4) 1,416 (3.3) 9,233 (25.2) 4,123 (18.7)
4 9,352 (9.2) 200 (0.5) 4,857 (13.2) 4,295 (19.4)
5 3,017 (3.0) 2 (0.0) 1,102 (3.0) 1,913 (8.7)
Inpatient at time of stroke (%) 6,184 (6.1) 1,426 (3.3) 2,211 (6.0) 2,547 (11.5) 2 (0.0)
NIHSS at arrival (median [Q1-Q3]) 3.0 [1.0–8.0] 2.0 [0.0–4.0] 4.0 [2.0–9.0] 13.0 [6.0–20.0] 43,474 (42.6%)
Type of stroke (%)
Ischemic (Reference) 87,594 (85.8) 39,720 (91.6) 31,905 (87.0) 15,969 (72.3) -
Hemorrhagic 13,511 (13.2) 3,282 (7.6) 4,492 (12.2) 5,737 (26.0) -
Unspecified 1,030 (1.0) 359 (0.8) 290 (0.8) 381 (1.7) -
Wake-up stroke (%) 18,635 (18.2) 8,683 (20.0) 6,495 (17.7) 3,457 (15.7) 18,729 (18.3)
Stroke alert activation (%) 35,277 (34.5) 14,014 (32.3) 12,883 (35.1) 8,380 (37.9) 1,319 (1.3)
Ambulance service to the hospital (%) 70,786 (69.3) 24,349 (56.2) 28,180 (76.8) 18,257 (82.7) 8,469 (8.3)
Hour of Admission (%) 4,021 (3.9)
00–04 (Reference) 4,332 (4.2) 1,723 (4.0) 1,508 (4.1) 1,101 (5.0)
04–08 5,852 (5.7) 2,553 (5.9) 1,891 (5.2) 1,408 (6.4)
08–12 29,094 (28.5) 12,591 (29.0) 10,127 (27.6) 6,376 (28.9)
12–16 27,870 (27.3) 12,371 (28.5) 10,317 (28.1) 5,182 (23.5)
16–20 19,396 (19.0) 8,204 (18.9) 7,190 (19.6) 4,002 (18.1)
20–24 11,570 (11.3) 4,632 (10.7) 4,219 (11.5) 2,719 (12.3)
Day of week of admission (%) 44 (0.04)
Sunday (Reference) 13,214 (12.9) 5,290 (12.2) 4,951 (13.5) 2,973 (13.5)
Monday 16,255 (15.9) 7,126 (16.4) 5,806 (15.8) 3,323 (15.0)
Tuesday 15,377 (15.1) 6,712 (15.5) 5,435 (14.8) 3,230 (14.6)
Wednesday 15,147 (14.8) 6,511 (15.0) 5,446 (14.8) 3,190 (14.4)
Thursday 14,740 (14.4) 6,348 (14.6) 5,263 (14.3) 3,129 (14.2)
Friday 14,446 (14.1) 6,149 (14.2) 5,105 (13.9) 3,192 (14.5)
Saturday 12,912 (12.6) 5,210 (12.0) 4,652 (12.7) 3,050 (13.8)