Table 2.
Association of the TyG index, lipid parameters, and glycemic with hypertension in total subjects using generalised estimation equation model (GEE)†
| Variable | Model 0‡ OR (95%CI) | p-value | Model 1§ OR (95%CI) | p-value | Model 2¶ OR (95%CI) | p-value |
|---|---|---|---|---|---|---|
| TyG index | ||||||
| Q1 | 1.0 | 1.0 | 1.0 | |||
| Q2 | 2.28 (2.19-2.37) | <0.001 | 1.56 (1.50-1.63) | <0.001 | 1.34 (1.28-1.40) | <0.001 |
| Q3 | 4.64 (4.45-4.83) | <0.001 | 2.35 (2.25-2.45) | <0.001 | 1.69 (1.61-1.78) | <0.001 |
| Q4 | 9.61 (9.22-10.02) | <0.001 | 3.96 (3.79-4.14) | <0.001 | 2.30 (2.19-2.43) | <0.001 |
| Q5 | 21.8 (20.91-22.80) | <0.001 | 7.88 (7.52-8.26) | <0.001 | 3.35 (3.15-3.57) | <0.001 |
| Per-1 | 6.11 (5.97-6.26) | <0.001 | 3.54 (3.45-3.63) | <0.001 | 2.64 (2.53-2.75) | <0.001 |
| TG/HDL-C ratio | ||||||
| Q1 | 1.0 | 1.0 | 1.0 | |||
| Q2 | 1.99 (1.92-2.07) | <0.001 | 1.41 (1.36-1.47) | <0.001 | 1.24 (1.19-1.30) | <0.001 |
| Q3 | 3.72 (3.58-3.87) | <0.001 | 2.01 (1.93-2.09) | <0.001 | 1.45 (1.38-1.51) | <0.001 |
| Q4 | 6.84 (6.57-7.12) | <0.001 | 3.05 (2.92-3.19) | <0.001 | 1.68 (1.60-1.76) | <0.001 |
| Q5 | 12.8 (12.3-13.4) | <0.001 | 5.27 (5.03-5.52) | <0.001 | 1.86 (1.76-1.95) | <0.001 |
| Per-1 | 2.54 (2.50-2.59) | <0.001 | 1.84 (1.80-1.87) | <0.001 | 1.19 (1.16-1.21) | <0.001 |
| TG, mmol/L | ||||||
| Q1 | 1.0 | 1.0 | 1.0 | |||
| Q2 | 1.96 (1.89-2.03) | <0.001 | 1.37 (1.32-1.42) | <0.001 | 1.12 (1.07-1.17) | <0.001 |
| Q3 | 3.60 (3.46-3.73) | <0.001 | 1.95 (1.87-2.03) | <0.001 | 1.28 (1.22-1.33) | <0.001 |
| Q4 | 6.59 (6.34-6.84) | <0.001 | 3.01 (2.89-3.14) | <0.001 | 1.50 (1.42-1.57) | <0.001 |
| Q5 | 12.8 (12.3-13.3) | <0.001 | 5.36 (5.13-5.60) | <0.001 | 1.67 (1.58-1.78) | <0.001 |
| Per-1 | 2.84 (2.79-2.89) | <0.001 | 2.02 (1.98-2.06) | <0.001 | 1.23 (1.19-1.27) | <0.001 |
| TC, mmol/L | ||||||
| Q1 | 1.0 | 1.0 | 1.0 | |||
| Q2 | 1.12 (1.07-1.17) | <0.001 | 1.22 (1.18-1.26) | <0.001 | 1.09 (1.05-1.14) | <0.001 |
| Q3 | 1.28 (1.22-1.33) | <0.001 | 1.46 (1.41-1.52) | <0.001 | 1.20 (1.14-1.26) | <0.001 |
| Q4 | 1.50 (1.42-1.57) | <0.001 | 1.72 (1.66-1.79) | <0.001 | 1.28 (1.20-1.36) | <0.001 |
| Q5 | 1.67 (1.58-1.78) | <0.001 | 2.27 (2.18-2.36) | <0.001 | 1.45 (1.33-1.58) | <0.001 |
| Per-1 | 1.49 (1.47-1.51) | <0.001 | 1.37 (1.35-1.39) | <0.001 | 1.76 (1.65-1.88) | <0.001 |
| LDL-C, mmol/L | ||||||
| Q1 | 1.0 | 1.0 | 1.0 | |||
| Q2 | 0.90 (0.87-0.92) | <0.001 | 0.96 (0.93-1.00) | 0.04 | 0.98 (0.94-1.02) | 0.27 |
| Q3 | 1.10 (1.07-1.13) | <0.001 | 1.07 (1.03-1.11) | <0.001 | 1.03 (0.99-1.07) | 0.15 |
| Q4 | 1.43 (1.38-1.47) | <0.001 | 1.20 (1.16-1.25) | <0.001 | 1.08 (1.04-1.13) | <0.001 |
| Q5 | 2.02 (1.95-2.08) | <0.001 | 1.49 (1.43-1.54) | <0.001 | 1.24 (1.19-1.29) | <0.001 |
| Per-1 | 1.40 (1.38-1.42) | <0.001 | 1.21 (1.19-1.23) | <0.001 | 1.12 (1.10-1.14) | <0.001 |
| HDL-C, mmol/L | ||||||
| Q1 | 1.0 | 1.0 | 1.0 | |||
| Q2 | 0.70 (0.68-0.72) | <0.001 | 0.84 (0.81-0.87) | <0.001 | 1.08 (1.04-1.12) | <0.001 |
| Q3 | 0.47 (0.45-0.48) | <0.001 | 0.68 (0.65-0.70) | <0.001 | 1.04 (1.00-1.09) | 0.07 |
| Q4 | 0.32 (0.31-0.33) | <0.001 | 0.55 (0.53-0.58) | <0.001 | 0.99 (0.94-1.04) | 0.64 |
| Q5 | 0.23 (0.22-0.24) | <0.001 | 0.47 (0.45-0.49) | <0.001 | 0.92 (0.86-0.99) | 0.02 |
| Per-1 | 0.18 (0.17-0.18) | <0.001 | 0.41 (0.39-0.43) | <0.001 | 0.88 (0.81-0.96) | <0.001 |
| FPG, mmol/L | ||||||
| Q1 | 1.0 | 1.0 | 1.0 | |||
| Q2 | 0.53 (0.52-0.55) | <0.001 | 0.71 (0.68-0.73) | <0.001 | 0.77 (0.74-0.80) | <0.001 |
| Q3 | 0.86 (0.83-0.89) | <0.001 | 0.98 (0.95-1.01) | 0.25 | 0.96 (0.93-1.00) | 0.03 |
| Q4 | 1.52 (1.47-1.57) | <0.001 | 1.44 (1.39-1.49) | <0.001 | 1.27 (1.22-1.31) | <0.001 |
| Q5 | 4.10 (3.97-4.23) | <0.001 | 2.65 (2.56-2.74) | <0.001 | 1.90 (1.83-1.97) | <0.001 |
| Per-1 | 1.16 (1.14-1.18) | <0.001 | 1.12 (1.10-1.13) | <0.001 | 1.07 (1.06-1.08) | <0.001 |
†
Model was adjusted for the variables of repeated years of medical check-up based on all medical check-up participants by using GEE.
‡
Model 0: adjusted for nothing.
§
Model 1: adjusted for age and sex.
¶
Model 2: adjusted for age; sex; center; body mass index; total cholesterol; total triglyceride; high-density lipoprotein cholesterol; low-density lipoprotein cholesterol; fasting plasma glucose; uric acid.